A method for the determination of trace amounts of off-flavor compounds such as 2-methyl isoborneol (MIB), geosmin and 2,4,6-trichloroanisole (TCA) in drinking water is described based on dynamic headspace coupled to selectable one-dimensional or two-dimensional gas chromatography - mass spectrometry with...

Stir Bar Sorptive Extraction (SBSE) is an innovative and efficient method [1] for the extraction of drugs and pharmaceuticals from blood-, urine- and tissue samples in a forensic toxicology laboratory. As shown in this application note and earlier publications [2,3,4], SBSE is an effective screening tool for drugs and pharmaceuticals in biological fluids and tissue.

Fruit and vegetable extracts that are produced following the well established QuEChERS method [1,2] typically contain a significant amount of involatile matrix material. After several injections of such extracts into the GC, sufficient matrix residue will be present in the GC inlet liner to lower...

The Deepwater Horizon oil rig explosion and the subsequent massive oil spill is expected to be the worst offshore oil catastrophe in United States history and is now beginning to impact fragile ecosystems, air and water quality, and food supplies.

This method uses a QuEChERS (quick, easy, cheap, effective, rugged, and safe) single-step acetonitrile (ACN) extraction and salting out liquid-liquid partitioning to extract PAHs from seafood tissue. Stir Bar Sorptive Extraction (SBSE) is then used as a combined cleanup and concentration step,...

Direct injection for gas chromatographic profiling of alcoholic beverages is usually preferable, but where spirits and liquors contain appreciable amounts of non-volatile material, some mode of pre-treatment may be required to avoid both inlet and column contamination.

USP Residual Solvents [1] is a general chapter in the US Pharmacopeia that describes a headspace gas chromatographic method for the determination of residual solvents in pharmaceutical products, active ingredients, and excipients. As originally written, it described parameters used with balanced-pressure or pressure loop based headspace instruments. Recent updates [2] have included parameters for syringe based systems.

Accurate qualitative and quantitative analysis of perfumed or flavored products is essential to the flavor and fragrance industry. Especially when unknown samples need to be analyzed traditional methods of GC analysis often lead to only vague results and often require time consuming...

A novel stir bar sorptive extraction (SBSE) procedure termed sequential SBSE was developed. Compared to conventional SBSE, sequential SBSE provides more uniform enrichment over the entire polarity/volatility range for organic pollutants at ultra-trace levels in water.

Static (equilibrium) headspace sampling is commonly used for GC determination of volatiles in solid and liquid samples. Since this technique relies on the analyte partitioning between the sample and headspace and uses a fixed injection volume it may not provide adequate detection limits, particularly for higher molecular weight, higher boiling analytes, and for polar analytes in aqueous samples.