SPExos procedure

Before transferring the sample to the SPExos online SPE unit the MultiPurpose Sampler MPS can perform a wide range of sample preparation steps including addition of standards, filtration, evaporation, dilution or centrifugation.

The MPS transfers the sample directly to SPExos. Depending on the method SPExos cartridges can be conditioned before loading. After the analytes are trapped on the solid phase material inside the cartridge, washing steps can be performed for further removal of matrix compounds.

Due to the small amount of solid phase elution can be performed using small eluent volumes: No further concentration steps are needed, 100 % analyte can be transferred directly to the LC column.

During the LC/MS analysis run the MPS starts the sample preparation of the next sample providing maximum productivity and throughput.